The methylation levels of the two most strongly associated LC-AwS CpG sites: cg05575921-AHRR and cg03636183-F2RL3, were not associated with lung cancer risk in never smokers (OR = 0.27 (95% CI: 0.03–2.14) and 1.22 (95% CI: 0.32–4.68), respectively. Here, AHRR is linked to lung cancer.