STAT3 and type 1 diabetes mellitus: In an animal model of STZ-induced type I diabetes, after 30 min ischaemia and 2 h reperfusion there was a significant reduction in phosphorylated STAT3 (Tyr705) levels in the diabetic group compared to the nondiabetic control group (tissue samples were collected from the ischaemic zone of the myocardium) [93].