STAT3 and type 2 diabetes mellitus: In addition, the phosphorylated STAT3 (Tyr705) and total STAT3 levels were significantly reduced in a type II diabetes model, i.e., in isolated perfused hearts of leptin receptor null, homozygous db/db mice subjected to ischaemia/reperfusion compared to wild-type hearts subjected to ischaemia/reperfusion [95].