Furthermore, the flavonoid irigenin targets the TRAIL signaling pathway leading to apoptosis in gastric cancer, with the enhancement of FAS-associated protein with death domain (FADD), death receptor 5 (DR5) and Bax proapoptotic proteins [133], a way targeted also by pinostrobin [134], apigenin [135], kaempferol [136]. The gene discussed is TNFRSF10B; the disease is gastric cancer.