TP53 and ovarian cancer: The p53 (TP53) signatures were present in the fallopian tubes of 19% (12/64) and 33% (19/58) of women who are at average risk of ovarian cancer, compared with 11% (19/176) and 24% (10/41) of high-risk women undergoing risk-reducing salpingo-oophorectomy (RRSO) [101,109].