High VEGFR-1 expression in epithelial tumor cells of breast cancers and non-small cell lung carcinomas is associated with short survival [19,20,21], but low VEGFR-1 expression in tumor cells of cholangiocarcinomas and diffuse large B cell lymphomas (DLBCL) is also associated with short survival [22,23]. This evidence concerns the gene FLT1 and cholangiocarcinoma.