The addition of crenolanib (dosage of 100 mg, three times/day) to standard “7 + 3” induction chemotherapy produced the following results in patients with newly diagnosed AML patients bearing a FLT3 mutation: overall, 96% of patients achieved a CR with full count recovery, while 88% achieved CR after one cycle of induction; with a median follow up of six months, only three patients aged >60 years relapsed [69]. The gene discussed is FLT3; the disease is acute myeloid leukemia.