In that context, the behavior exhibited by the different cell lines could be related to the p53 status of the cells, since in prostate cancer, deregulation of p53, a transcription factor shown to be involved in DNA-damage-induced apoptosis, DNA repair, and cell cycle arrest, has been demonstrated to play a role in the development of the advanced stage of the disease [38,39]. Here, TP53 is linked to prostate cancer.