Downregulation of IGF1 receptor (IGF1R) expression or blocking IGF1R signaling leads to tumor growth suppression (Sachdev & Yee 2007, Ryan & Goss 2008) and increases the susceptibility of tumor cells to chemotherapies (Tao et al. 2007, Chitnis et al. 2008, Ryan & Goss 2008). This evidence concerns the gene IGF1R and neoplasm.