Despite the many different protumor roles attributed to FGF2 signaling (reviewed by Turner and Grose, 2010), a set of articles unequivocally demonstrate that FGF2 can also induce cytostatic and cytotoxic responses in different cancer cells, both in vivo and in vitro (Fogarty et al., 2007; Sturla et al., 2000; Wang et al., 1998; Williamson et al., 2004). Here, FGF2 is linked to cancer.