PKN3 and neoplasm: The primary tumors were surgically removed at days 21 and 22 after inoculation for the SCpkn3−/− cell lines (+PKN3 WT, +mCherry, and +PKN3 mPR, respectively) and at day 16 in parental SC cells inducibly expressing mCherry owing to large tumor sizes (Fig. 8E,F).