This is consistent with the unsatisfactory results obtained by combining CXCR4 inhibition with further mobilization through G‐CSF.24 Future studies should investigate factors other than CXCR4 that regulate AML cell migration and/or survival in vivo and whether additional interventions may complement chemotherapy and CXCR4 inhibition. This evidence concerns the gene CSF3 and acute myeloid leukemia.