Indeed, C6 glioma cells exhibit increased ROS levels (5.7 fold; 752.56 vs. 191.95 nmol DCF/mg of protein) and SOD activity (1.98 fold; 479.41 vs. 338.45 U/mg of protein), while CAT activity was decreased (3.4 fold; 5.05 vs. 16.61 U/mg of protein) when compared to primary astrocyte cultures. This evidence concerns the gene SOD1 and central nervous system cancer.