To compare the oncogenic properties between cell lines, MKN45 (poorly differentiated adenocarcinoma) with high-gank expression seemed showing higher proliferation abilities than MKN74 (highly differentiated adenocarcinoma) with low-gank expression (Figures 2(a)–2(d)), which also hinted that gankyrin might promote the process of gastric cancer development. This evidence concerns the gene PSMD10 and adenocarcinoma.