In this study, by using the data from the Cancer Genome Atlas (TCGA)—Lung Cancer, we examined the expression profile of UBE2D1 in the two major subtypes of non-small-cell lung cancer (NSCLC) lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) and its prognostic value in these subtypes. Here, UBE2D1 is linked to non-small cell lung carcinoma.