These authors also performed multivariate analysis of 164 NSCLC patients to compare the tumor pathologic stage (IA, IB, IIA, IIB, IIIA, IIIB), patient age, sex, smoking status, histology (adenocarcinoma vs. squamous cell carcinoma) and EGFR status and found EGFR mutations and histology to be independent variables for high PD-L1 expression (P = 0.027 and P = 0.046, respectively). This evidence concerns the gene EGFR and adenocarcinoma.