CXCL1 and neoplasm: CXCR1/2 is expressed on melanoma cells, MDSC and neutrophils and sustains tumor immunosuppression, tumor growth, angiogenesis and tumor dissemination in response to CXCL1, CXCL2 or CXCL8 (107, 108, 159–164) (Tables 1, 2).