Of which, CCND1, CDC42, YAP1, RPA1 and RAD51 integrated the most relevant communities, CCND1, CDC42, ITGAV, TFDP1 and TRRAP integrated the OncoPPi BC network, CCND1, CDC42, RPA1, RAD51, CDK1, SMC2, XRCC6, ITGAV, PLK1, MCL1, BCL2L1, ITGB5, RBX1, PPP2RIA and CRKL integrated the BC integrated network, and finally, all 54 genes were part of the Consensus genes. The gene discussed is PLK1; the disease is breast cancer.