As for the CD45 analysis, we used unique fluorescence thresholds (DAPI: 500 g.v.l; Cy3: 2, 500 g.v.l; FITC: 1,500 g.v.l; maxima at 65,536 g.v.l) to detect and classify these cell populations in each iROI (Fig. 7b: mucosa, 7c: lymphoid follicle, 7d: tumor). The gene discussed is PTPRC; the disease is neoplasm.