FGFR2 and cancer: The presented results should be framed in the unique clinical phenotype of patients with FGFR2 gene aberrations, exhibiting peculiar pathological (prominent intraductal cancer growth) and clinical features (longer survival).31 Although a more indolent disease course of these patients may be attributable to a less aggressive biology, with consequent prolongation of PFS in patients harbouring FGFR2 translocation regardless of targeted therapy, there are no data about PFS in the second-line setting in this cohort.