ATP6V0C and colorectal cancer: The IDF-11774-bafilomycin A1 combined treatment induced different responses in various colorectal cancer cell lines; therefore, we conducted isobologram analysis to characterize the relationship between IDF-11774 and the ATP6V0C inhibitors, bafilomycin A1 and concanamycin A, or the autophagosome–lysosome fusion inhibitor, chloroquine, to identify genetic marker(s) in the cell lines (Fig. 3d).