IHC analysis showed PTPN6 negativity in 63.7% (93/147) of all PTCL patient tissues with 62% (35/56) of PTCL-NOS, 60% (14/23) of ALK-neg ALCL, 86% (13/15) of ALK-pos ALCL, and 42% (9/21) of AITL analyzed were PTPN6 negative (Fig. 3b). Here, PTPN6 is linked to mature T-cell and NK-cell non-Hodgkin lymphoma.