When meta-analyzed with published case-control datasets, we found strong evidence that LoF variants in NMDAR complex genes were associated with schizophrenia (p = 1.6 × 10–4) (Figure 2 and Table S4 in Supplement 2), but weaker evidence for association with ARC complex genes (p = .047) (Figure 2 and Table S4 in Supplement 2). The gene discussed is ARC; the disease is schizophrenia.