MET and neoplasm: Using total liver weight as well as liver/body weight ratio as the measurement of tumor burden, all c-Met/β-cateninS45Y or c-Met/∆N90-β-catenin injected mice had significantly increased tumor burden when compared to wild-type mice (Fig. 1b and c), whereas the overall tumor burden was similar between c-Met/β-cateninS45Y and c-Met/∆N90-β-catenin mouse cohorts (Fig. 1b and c).