Increased γH2AX expression was found in tumour xenografts of PC-3-EpCAM-KD CaP cells compared to PC-3-EpCAM-scr group after RT (Additional file 3: Table S3), suggesting that sensitisation of CaP to RT could be mediated by KD of EpCAM in vivo. The gene discussed is EPCAM; the disease is neoplasm.