In s.c. model, all xenograft tumours (n = 10) became palpable from the third week after cell inoculation in PC-3-EpCAM-KD group while all xenograft tumours (n = 10) became palpable from the second week after cell inoculation in PC-3-EpCAM-scr group. The gene discussed is EPCAM; the disease is neoplasm.