EPCAM and neoplasm: To evaluate the effect of EpCAM on tumour-bearing mice survival, Kaplan-Meier curves demonstrated that KD of EpCAM improved median survival (MS) of tumour-bearing mice (PC-3-EpCAM-KD) by 21.5 days compared with the control group mice (PC-3-EpCAM-scr s.c. xenografts) (HR = 26.94, CI95% 4.317–168.1, p = 0.0004) (Fig. 5a).