Accordingly, a significant difference in final tumor weight was detected between Dox-treated and untreated PKD1-c1 clones (PKD1-c1/−Dox and PKD1-c1/+Dox) with a higher tumor weight for PKD1-c1/+Dox (**p < 0.01), while there were no statistically significant difference among other groups (p > 0.05) (Fig. 5c-d). Here, PKD1 is linked to neoplasm.