Additionally, in a study to verify the effects of cannabinoid receptor 2 (CB2) genic deletion on pulpitis-related pain, wild-type (WT) mice, submitted to unilateral pulp exposure of the first upper and lower molars, presented a reduction in body weight after 2 days following surgery, with a slight reduction of food consumption at 1 day [47]. The gene discussed is CNR2; the disease is pulpitis.