PPARG is a known regulator of glucose metabolism, thereby its synthetic ligands includes many members of the antidiabetic thiazolidinedione (TZD) drug class, glitazones and telmisartan, an antagonist of the type-1 angiotensin II receptor (AGTR1/AT1) used in the treatment of hypertension [91]. Here, AGTR1 is linked to hypertensive disorder.