Data mining of the DisGeNET database by associated disease clustering having as input the 16 proteins from Table 2 showed association of MPO, APOA1, APOB and ADIPOQ with myeloperoxidase deficiency, hypertensive disease, hypercholesterolemia, hyperlipidemia and hypoalphalipoproteinemia. The gene discussed is MPO; the disease is Hypercholesterolemia.