Indeed, hepatocytes produced albumin and urea,38 LSEC displayed characteristic fenestrae and sinusoidal Ac‐LDL endocytosis,39, 40, 41 HMΦ responded to LPS stimulation, especially those isolated from Ch animals, which is in accordance with recent in vivo data on acute on chronic liver failure,34 and HSC expressed their characteristic activation marker α‐SMA. Here, ACTA1 is linked to chronic liver failure.