Population-based studies have shown that the APOL1 variants G1 [rs73885319 AdeltaG (S342G) and rs60910145 TdeltaG (M384I)] especially rs73885319 AdeltaG (S342G)7 and G2 [rs71785313 TTATAA → del (NYK388K)] are strongly associated with increased risk for chronic kidney diseases in individuals of sub-Saharan African ancestry8. Here, APOL1 is linked to chronic kidney disease.