MMP2 and stroke disorder: Indeed, expression of MMP-2 was 100-fold higher (4273 pg/mg), expression of MMP-3 was almost 3000-fold higher (15,059 pg/mg), and expression of MMP-8 was 500-fold higher (12,923 pg/mg) at eight weeks post stroke in the area of liquefactive necrosis compared to naïve brain tissue.