There was a significant difference in the expression of BRAF between the BRAF (V600E) MT and WT (p = 0.008) in colon cancers; and there was a significant difference in the expression of EGFR between the NRAS MT and WT (p = 0.021) in rectal cancers (Tables S1, S2). Here, NRAS is linked to malignant colon neoplasm.