SNP2 is located in an intron of the gene ARVCF and three additional genes are in linkage: COMT, TXNRD2, and TANGO2. Previously, SEZ6L, ARVCF, COMT, and TXNRD2 have been associated with social disorders and schizophrenia in humans (Chapman et al., 2015; Mas et al., 2010; Sanders et al., 2005; Xu et al., 2013). This evidence concerns the gene COMT and schizophrenia.