As summarized in Table 3, extensive induction of apoptosis was observed only in two of the 14 cell lines across the sarcoma panel, both of which were derived from chromosomal translocation-positive sarcomas (EWSR1-FLI1 in Ewing's sarcoma RD-ES cell line and PAX3-FOXO1 in alveolar rhabdomyosarcoma SJCRH30 cell line, respectively) [43, 44]. The gene discussed is FOXO1; the disease is Ewing sarcoma.