MiR-181d-5p co-transfection determined a 20% decrease of the luciferase activity of pGL3-LUCAT1 vector with respect to negative control co-transfected cells (Student's t-test, p=0.001), demonstrating a sponge effect exerted by LUCAT1 on miR-181d-5p in HCC cells (Figure 6C). Here, LUCAT1 is linked to hepatocellular carcinoma.