We thus tested a panel of biomarkers of EMT in HCC cell lines as well as in HCC tissues (60 patients), including CDH1 (E-cadherin), CDH2 (N-Cadherin), CTNNB1 (beta-catenin), TCF7L2 (wnt signaling), VIM (Vimentin), ZEB1, ZEB2, TWIST, SNAIL1 and SNAIL2. This evidence concerns the gene TCF7L2 and hepatocellular carcinoma.