CD19 and diffuse large B-cell lymphoma: CARs specific for CD19 (also known as B-lymphocyte antigen CD19) have induced high remission rates (over 80%) in patients with treatment-refractory acute lymphocytic leukaemia (ALL) or diffuse large B-cell lymphoma.9,10 Although it still remains to be proven, it is very likely that these remission rates will also prolong overall survival for these otherwise untreatable patient populations.