CCL2 and infection: In particular, in MR1−/− mice we detected significantly lower amounts of monocyte chemotactic protein 1 (MCP-1/CCL2) and IL-6 following infection with 100 PFU of PR8, and of RANTES/CCL5 following 5000 PFU of X-31 with similar trends observed with both virus strains for each of the inflammatory mediators detected (Supplementary Fig. 6).