Certain chemokines and growth factors, including vascular endothelial growth factor (VEGF), interleukin-8 (IL-8), transforming growth factor-β (TGF-β), and neurotrophin-3 (NT-3) released from mature glioma cells, have been reported to mediate the tropism of MSCs for gliomas [25–27]. This evidence concerns the gene TGFB1 and central nervous system cancer.