In our study, we demonstrated that specific chemokines, such as MCP-1/CCL2 and SDF-1/CXCL12 (receptors CCR2 and CXCR4 expression in MSCs from hUCB), mediate the migration of MSCs toward CD133+ GBM cells in vitro. The gene discussed is CXCR4; the disease is glioblastoma.