In the entire group of HD patients tested for adropin, significant correlations were found between the circulating adropin levels and TG level (r = − 0.302, P = 0.0006), TG/HDL cholesterol ratio (r = − 0.301, P = 0.0006), and BMI (r = − 0.316, P = 0.0004). The gene discussed is ENHO; the disease is Huntington disease.