CCL5 and hepatocellular carcinoma: The synthetic polymers OTR4120 or OTR4131 (Figure 7b) were shown to directly bind the proinflammatory basic chemokine CCL5 (regulated on activation, normal T cell expressed and secreted; RANTES) and to inhibit the the CC-chemokine-stimulated migration and invasion of the human hepatoma cell line HuH7 [244].