MRC1 and cancer: The study showed the loss of MMR protein expression was reported in 44 (19.2%) patients with EC, which was within the range (19–38%) reported in other studies.[16,25,26] This study did not aim to determine the methodologies to identify LS, but the loss of MMR protein expression was found to be associated with an increased positive family history of cancer (adjusted OR = 4.81, 95% CI: 2.14–8.83).