Kimberly Resnick thought IHC evaluation of tumor specimens for MMR protein expression after single gene sequencing for patients with endometrial cancer is a cost-effective strategy for detecting LS.[29] In China, restricted by the medical resources, IHC testing of MMR protein were usually concentrated in tertiary urban hospitals and largely performed according to the preferences of clinicians in China. The gene discussed is MRC1; the disease is neoplasm.