Regarding the laboratory test results before treatment, erythrocyte sedimentation rate (ESR) of seven patients ranged from 1 to 111 mm/h (71.4% above the normal range), C-reactive protein (CRP) level of 10 patients ranged from 0.51 to 181.26 mg/L (80% above the normal range), and white blood cell count of 12 patients ranged from 3.59 to 17.26×109/L (33.3% with leukocytosis and elevated neutrophil ratio). The gene discussed is CRP; the disease is Increased total leukocyte count.