PVT1 and hepatocellular carcinoma: We first found that multiple lncRNAs achieved a higher accuracy than single lncRNA with sensitivity of 0.898 (0.82-0.944) versus 0.862 (0.825-0.892), specificity of 0.886 (0.845-0.916) versus 0.805 (0.76-0.844), and AUC of 0.94 versus 0.902, suggesting that existing an effective lncRNA panel such as RP11-160H22.5, XLOC_014172, and LOC149086, or Linc00152, RP11-160H22.5, and XLOC_014172, or HULC and Linc00152, or uc001ncr and AX800134, or PVT1 and uc002mbe.2 could perform combined diagnosis of HCC (Figure 4(a)).