MYC and gastric neoplasm: The MYC oncogene, located at 8q24, is a key oncogene in gastric carcinogenesis, and an increase in both copy number and mRNA expression was classified as one of the driver mutations in gastric tumors [3]. MYC amplification and overexpression are present in 6-58% of all sporadic gastric tumors [4–6], being more frequent in Brazilian samples [7–9], usually as a result from gene amplification and chromosomal translocations [2, 10].