As shown in Fig. 1A–C, the expression of the epithelial marker E‐cadherin was significantly decreased in glioma cells with TGF‐β treatment in a concentration‐dependent manner, while the expression of the mesenchymal marker Slug, which was also the downstream effector of TGF‐β signaling 11, displayed the opposite effect. This evidence concerns the gene TGFB1 and central nervous system cancer.