Thioredoxin interacting protein (TXNIP), also called thioredoxin‐binding protein‐2 or vitamin D3 up‐regulated protein 1, was originally identified as a molecule up‐regulated in HL‐60 leukemia cells by 1,25‐dihydroxyvitamin D3 treatment 1. This evidence concerns the gene TXNIP and leukemia.