PHLDA1 and gastric cancer: To investigate the role of PHLDA1 on gastric cancer cell survival ability, firstly, SGC-7901, MGC-803, HGC-27, MKN-45, MKN-28 gastric cancer cells and human stomach epithelial cells (HPSEC) were used to examine PHLDA1 expression, it was found that PHLDA1 expression was lower in MKN-28 and HGC-27 cell lines than the other cell lines (Fig. 1a).