SLAMF7 and Miyoshi myopathy: The mechanisms of action of elotuzumab are: direct activation of NK cells via the EAT-2-mediated signaling pathway by binding with SLAMF7 on NK cells; induction of NK-mediated antibody-dependent cell-mediated cytotoxicity (ADCC); and interruption of the SLAMF7-mediated adhesion of MM cells to BM stromal cells [19, 20].