APOE and hemorrhage: Furthermore our finding of a higher prevalence of APOE epsilon 2 allele and APOE epsilon 4 allele in subjects with spontaneous intracerebral haemorrhage and β-amyloid accumulation on temporal artery biopsy specimen could suggest that temporal artery should be considered as a possible arterial site of amyloid accumulation thus to represent a candidate diagnostic marker of CAA in subjects with predisposing APOE genotypes.