TNF and rheumatoid arthritis: Informative gene sets include genes (NFKBIA, CCL4, IL8, IL1B, TNFAIP3, PDE4B, PPP1R15A, and ADM) involved in different pathways and cellular processes such as TNFα signaling via NFκB; Van Baarsen et al. performed microarray of PBMC of RA patients before and 1 month after infliximab treatment [26].