The inverse relationship between activated T cells: CD4+CD25+CD69+IFNγ+IL-2−TNFα− (r = −0.322, p = 0.039); CD8+CD25+CD69+IFNγ+ (r = −0.371, p = 0.016); CD8+CD25+CD69+ IFNγ+IL-2−TNFα− (r = −0.360, p = 0.020); and LD Treg Ki67+HLA-DR+ (r = −0.332, p = 0.033) and delayed TCC also makes these cell populations possible candidates as predictors of TCC. This evidence concerns the gene CD4 and tarsal-carpal coalition syndrome.